Where the trial data comes from
Trial listings come from ClinicalTrials.gov (opens in a new tab), the U.S. government’s public registry of clinical research. This site does not run trials and has no relationship with trial sponsors.
The listings here are a copy of the registry. A newly opened site or a trial that has stopped recruiting may not be reflected here yet. Always check the official trial page.
We check that a listing concerns Alzheimer’s, dementia, related conditions, or mild cognitive impairment. This includes relevant prevention and caregiver research. A broad registry search can also return unrelated studies; those are kept out of these lists. When a study’s connection is unclear, it appears in “Can’t tell” with a note. This check can miss relevant studies, so you can also search the registry directly.
How a computer reads eligibility criteria
A computer reads each trial’s public criteria to look for details such as study-partner requirements, imaging, and lumbar punctures. The sort also uses the trial’s listed age range and recruiting sites.
It can miss or misread a requirement. An unusual phrase or an unclear listing can change the result. The lists are a starting point for a conversation.
Location matching is approximate and based on U.S. states. It does not calculate driving distance. We do not currently use relationship or diagnosis stage to sort trials, so we no longer ask for them. A coordinator still needs to check diagnosis-specific criteria.
How accurate it actually is
In a manual check of 40 trials, the system found 8 of the 12 study-partner requirements and missed 4. Every study-partner requirement it flagged in that sample was correct.
This is one limited check, not an overall accuracy score. If a study partner is not mentioned here, that does not mean one is not needed. Always ask.
What the three lists mean
Worth asking about — nothing in the criteria we could read appears to conflict with your answers.
Can’t tell — ask your doctor — the criteria could not be read reliably, or the study’s connection to dementia needs clarification. We show these trials so uncertainty does not make them disappear.
Probably not — a specific detail appears to conflict with your answers. Read the reason and ask the coordinator whether it applies. The listing is still available to you.
The one rule this whole site runs on
This site never tells you that you or your family member are eligible or ineligible for a trial. It only sorts trials by what their public listing says.
Call the coordinator listed on the trial’s official page to find out about taking part.